Familial Pyoderma Gangrenosum: About 2 cases

نویسندگان

  • Nabil Bel Feki
  • Monia Smiti-Khanfir
  • Fatma Said
  • Imed Ben Ghorbel
  • Thouraya Ben Salem
  • Mounir Lamloum
  • Amira Hamzaoui
  • Mohamed Habib Houman
چکیده

Pyoderma gangrenosum occurrence in a familial pattern is extremely rare. We report pyoderma gangrenosum in two Tunisian siblings with onset respectively at 28 and 26 years old. The initial lesion was a pustule that breaks down to form an ulcer with an erythematous border. Treatment with oral corticosteroids induced an excellent clinical response. This familial clustering suggests a possible genetic role in the development of pyoderma gangrenosum in some cases.

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تاریخ انتشار 2015